Compositions and method for enhancement of the transdermal flux of albuterol with a combination of 1-dodecyl-azacyclopheptan-2-one and urea
US4699777A · kind A · utility
10Cited by
6References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 21, 1985 |
| Grant date | Oct 13, 1987 |
| Priority date | — |
| Expiry date | Aug 21, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A topical albuterol composition having superior transdermal flux containing various amounts of albuterol, 1-dodecyl-azacycloheptan-2-one and urea in a non-aqueous environment. The enhancement observed in albuterol skin penetration indicates that a therapeutically effective amount of albuterol can be delivered through skin using these formulations. The compositions can be administered topically as a cream, lotion or via a transdermal device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.