Method of producing monoclonal anti-idiotype antibody
US4699880A · kind A · utility
123Cited by
3References
6Claims
0Family size
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Key dates
| Filing date | Sep 25, 1984 |
| Grant date | Oct 13, 1987 |
| Priority date | — |
| Expiry date | Sep 25, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/804
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for determining the presence of an antigen in a liquid sample. The method includes incubating the sample with an antibody which specifically binds an epitope on the antigen in the presence of a given quantity of an anti-idiotype antibody which specifically binds an epitope on the hypervariable region of the antibody. Also, a method of producing a monoclonal anti-idiotype antibody by fusing lymphocytes from an animal in which a tumor capable of secreting idiotype antibodies has been grown, with myeloma cells.
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