Injectable aqueous solution containing hydrogensulfite and/or sulfite and anticancerous benzodiazepine compound
US4701325A · kind A · utility
62Cited by
1References
7Claims
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Key dates
| Filing date | Feb 15, 1984 |
| Grant date | Oct 20, 1987 |
| Priority date | — |
| Expiry date | Feb 15, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An alkali metal hydrogensulfite or sulfite is effective for controlling a local injury such as inflammation and vein injury occurring on the injection of an antitumor benzodiazepine compound of the formula ##STR1## wherein R.sub.1 denotes hydrogen atom, or acyl, carbamyl, or alkoxycarbonyl group; R.sub.2 denotes hydrogen atom or acyl group; and R.sub.3 denotes sulfinic acid rest, SO.sub.2 X, or sulfonic acid rest, SO.sub.3 X, X meaning hydrogen, alkali metal or alkaline earth metal. An aqueous solution containing the both can be administered by injection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.