Analytical compositions, elements and methods utilizing reduction of ferric ion chelates to form detectable dyes
US4701420A · kind A · utility
9Cited by
12References
9Claims
0Family size
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Key dates
| Filing date | Apr 1, 1985 |
| Grant date | Oct 20, 1987 |
| Priority date | — |
| Expiry date | Apr 1, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Ferric ion chelates are useful in analytical compositions, elements and methods for the determination of reductants, or other analytes which can produce a reductant. The ferric ion chelate is reduced to ferrous ion, which coordinates with a suitable ferrous ion coordinating ligand to form a colored complex. In particular, these compositions and elments are useful for detecting nicotinamide adenine dinucleotide, reduced form (NADH) or nicotinamide adenine dinucleotide phosphate, reduced form (NADPH), or an analyte (e.g. an enzyme) which produces NADH or NADPH in biological fluids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.