Long-acting matrix tablet formulations
US4704284A · kind A · utility
28Cited by
31References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 12, 1982 |
| Grant date | Nov 3, 1987 |
| Priority date | — |
| Expiry date | Aug 12, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2004
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical tablet which releases an initial burst of therapeutic agent and thereafter releases the agent at an essentially constant rate comprising an acid soluble therapeutic agent in an insoluble matrix, the tablet containing an acid insoluble, base soluble pharmaceutically acceptable component selected from polymers and fatty acids, a pharmaceutically acceptable organic acid and at least one pharmaceutically acceptable excipient, the component and the acid each being present in an amount of from about 1-25 percent by weight of the total composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.