Patent · US Expired

Composition and method for stabilization of dinucleotides

US4704365A · kind A · utility

5Cited by
2References
15Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 24, 1986
Grant dateNov 3, 1987
Priority date
Expiry dateFeb 24, 2006

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/108331
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A reduced dinucleotide, preferably nicotinamide adenine dinucleotide (NADH), is stabilized in an aqueous base liquid containing propylene glycol, boric acid and a buffer capable of buffering within a pH range of 8-11. The stabilized liquid contains greater than 50% (v/v) water. The remaining volume contains propylene glycol which has been chemically treated to remove oxidants. This reagent may be used by itself or in conjunction with an assay reagent system for use in the clinical laboratory.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.