Process for the preparation of acellular Bordetalla pertussis vaccine
US4705686A · kind A · utility
15Cited by
8References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 9, 1986 |
| Grant date | Nov 10, 1987 |
| Priority date | — |
| Expiry date | May 9, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention discloses a process for preparing an acellular Bordetella pertussis vaccine by passing culture supernatants or cellular extracts of B. pertussis through a column containing an ion exchange resin. The eluate from the column is detoxified and can then be employed by conventional means as a vaccine. The vaccine so produced has reduced toxicity due to the removal of endotoxin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.