Indene and naphthalene derivatives
US4705782A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 26, 1986 |
| Grant date | Nov 10, 1987 |
| Priority date | — |
| Expiry date | Mar 26, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C281/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to compounds of the general formula I ##STR1## wherein R.sub.1 represents one up to and including four, the same or different substituents selected from alkyl(1-6 C), alkoxy(1-6 C), hydroxy, halogen, NO.sub.2, CF.sub.3 or the group --NR.sub.5 R.sub.6, PA2 whereby two substituents taken together may also represent a methylene-dioxy group, PA1 X represents a member selected from ##STR2## --CH.sub.2 --CH.sub.2 -- and --CH.dbd.CH--, n has the value 0, 1 or 2, PA1 R.sub.3 represents one of the moieties: ##STR3## and R.sub.2, R.sub.4, R.sub.5 and R.sub.6 represent hydrogen or alkyl(1-6 C), and pharmaceutically acceptable salts thereof, suitable in the treatment of heartfailure.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.