Ischaemia or hypoxia controlling compositions containing pyridinecarboxylic acid esters
US4705794A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 28, 1983 |
| Grant date | Nov 10, 1987 |
| Priority date | — |
| Expiry date | Feb 28, 2003 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Pyridinecarboxylic acid esters of the formula ##STR1## in which R is an optionally substituted aryl or heterocyclic radical, PA1 R.sup.1 and R.sup.2 are hydrogen, alkyl, aryl, aralkyl, acyloxyalkyl or hydroxyalkyl, or R.sup.1 with X forms a carbonyl-containing heterocyclic ring, PA1 X is --CN, --CO--R.sup.4, --COOR.sup.5 or --SO.sub.2 R.sup.6, PA1 R.sup.4, R.sup.5 and R.sup.6 are various optionally substituted radicals, and PA1 R.sup.3 is different from R.sup.5 and is a substituted or interrupted hydrocarbon radical, or pharmaceutically acceptable salts thereof control the otherwise negative effects of ischaemia and/or hypoxia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.