Process for producing .beta.-carboline derivatives

US4705856A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventor

• Helmut Biere · Berlin, DE

Key dates

• Filing date: Oct 28, 1983
• Grant date: Nov 10, 1987
• Expiry date: Oct 28, 2003

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

.beta.-carbolines of formula I ##STR1## can be prepared by reacting an indole of formula II: ##STR2## with an azabutadiene of formula III ##STR3## in the presence of an acid at 50.degree.-200.degree. C.