Preparation of nitriles and thioamides of fused ring pyridine derivatives
US4707552A · kind A · utility
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Key dates
| Filing date | Sep 18, 1985 |
| Grant date | Nov 17, 1987 |
| Priority date | — |
| Expiry date | Sep 18, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/48
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Nitriles and thioamides of fused ring pyridine compounds such as 5,6,7,8-tetrahydroquinolines are prepared from metal derivatives of the starting compounds such as 8-lithio-5,6,7,8-tetrahydroquinolines which have been prepared by treating a 5,6,7,8-tetrahydroquinoline with a metal amide prepared in situ from a metal alkyl and an N-benzylidine-N-alkylamine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.