Novel aroylpyrroles, their production and their use in immunologic therapy
US4709051A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 24, 1986 |
| Grant date | Nov 24, 1987 |
| Priority date | — |
| Expiry date | Mar 24, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to novel aroylated derivatives of pyrrole. More particularly it provides the novel naphthoyl derivatives of pyrrolyl-2-carboxylic acid having the general formula I: ##STR1## wherein: R.sub.1 is a lower alkyl radical, a phenyl radical or a hydrogen; PA0 X is a hydrogen, a hydroxy or a methylsulphinyl group; PA0 Y is a hydrogen or together with A' a double bond; PA0 A is a hydrogen or a hydroxy; PA0 A' is a hydrogen or together with Y a double bond; PA0 B is a hydrogen or a hydroxy; PA0 B' is a hydrogen or together with C a double bond; PA0 C is a hydrogen or together with B' a double bond; PA0 C' is a hydrogen, a hydroxy or a methylsulphinyl group; PA0 with the proviso that X, Y, A, A', B, B', C and C' are not simultaneously a hydrogen. The compounds according to this invention, may exist in the free acid form or as a salt. They found a use in human or veterinary medicine in the form of pharmaceutical compositions for preventing or treating the immunological diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.