Process for the preparation of 4-phenylpyrrole derivatives
US4709053A · kind A · utility
5Cited by
3References
1Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 9, 1985 |
| Grant date | Nov 24, 1987 |
| Priority date | — |
| Expiry date | Sep 9, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparation of 4-phenylpyrrole derivatives of the formula I ##STR1## wherein R.sub.n, R.sub.1 and R.sub.2 are as defined in claim 1, which comprises reacting a phenacylamine of formula II ##STR2## with a compound of formula III EQU T--CH.dbd.CH--R.sub.1 (III) to give an intermediate of formula IV ##STR3## and cyclizing said intermediate, in the presence of a base, to give the compound I. Important intermediates and novel final products are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.