Process for the preparation of 4-benzyl aspartate

US4709086A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Merten Schlingmann · Königstein, DE
• Hans-Ullrich Hoppe · Hofheim, DE
• Walter Dursch · Königstein, DE

Key dates

• Filing date: Jun 9, 1986
• Grant date: Nov 24, 1987
• Expiry date: Jun 9, 2006

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C227/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

In the process for the preparation of 4-benzyl aspartate starting from dibenzyl aspartate and/or its salts only one benzyl group is selectively removed by catalytic hydrogenation. By setting up appropriate reaction conditions elimination takes place mainly of the benzyl group on the C.sub.1 atom of the compound. The desired product can be isolated from the reaction mixture by precipitation.