Sustained release tablets made from microcapsules
US4710384A · kind A · utility
102Cited by
10References
6Claims
0Family size
Inventor
Key dates
| Filing date | Jul 28, 1986 |
| Grant date | Dec 1, 1987 |
| Priority date | — |
| Expiry date | Jul 28, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0007
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A tablet for oral adminstration of a sustained-release medication is formed by compressing microcapsules of the active principle. The microcapsules are of a size range between about 5 and 300 microns and comprise particles of active principle coated with a thin, flexible layer of sustained release material. The sustained-release material contains about 15-30% by weight thereof of plasticizer and is coated in an amount corresponding to 10-25% of the weight of the active material. Excipients causing disintegration of the tablet after administration can be uniformly mixed with the microcapsules prior to compression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.