Isothiuronium salts
US4710578A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 25, 1985 |
| Grant date | Dec 1, 1987 |
| Priority date | — |
| Expiry date | Nov 25, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D303/48
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
According to the present invention there are provided isothiuronium salts of the general Formula I ##STR1## wherein R.sup.1 is C.sub.1-6 alkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, C.sub.3-6 cycloalkyl, aralkyl or aryl, the said groups being optionally substituted by one or more hydroxy, mercapto and/or halogen; PA1 R.sup.2 stands for hydrogen, C.sub.1-6 alkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl or C.sub.3-6 cycloalkyl; PA1 X represents an organic or inorganic anion/. The compounds and salts of the present invention can be prepared by reacting a compound of the general Formula II ##STR2## with an agent capable of introducing a R.sup.1 group. The compounds of the general Formula I exhibit antitumor and immunostimulant effect and are useful in therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.