Patent · US Expired

Dipeptides and process

US4710583A · kind A · utility

14Cited by
0References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 21, 1985
Grant dateDec 1, 1987
Priority date
Expiry dateOct 21, 2005

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P21/02
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Synthesis of phenylserine ester (a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and (b) via methyl benzoylacetate. Synthesis of hydroxy-aspertame or derivative by enzymatic coupling of phenylserine or derivative with aspertic acid or derivative. Hydrogenation of the coupled product to give as final product aspertame or analog with related processes and products.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.