Glycoproteinic conjugates having trivalent immunogenic activity
US4711779A · kind A · utility
41Cited by
5References
12Claims
0Family size
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Key dates
| Filing date | Jul 2, 1986 |
| Grant date | Dec 8, 1987 |
| Priority date | — |
| Expiry date | Jul 2, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/832
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Glycoproteinic conjugates having trivalent immunogenic activity obtained by binding, by a covalent bond, to a protein selected among CRM 197, tetanus toxoid, and pertussis toxin, at least an oligosaccharidic hapten derived from the capsular polysaccharide of a gram-positive bacterium and at least an oligosaccharidic hapten derived from the capsular polysaccharide of a gram-negative bacterium, and wherein said oligosaccharidic haptens are previously activated by introducing terminal esters.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.