Patent · US Expired

Hydrazinopyridazine compounds

US4711887A · kind A · utility

3Cited by
3References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 28, 1983
Grant dateDec 8, 1987
Priority date
Expiry dateMar 28, 2003

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D237/34
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Hydrazinopyridiazine derivatives of the formula: ##STR1## wherein A is alkylene, wherein either R.sup.1 is hydrogen and R.sup.2 is hydrogen, alkoxycarbonyl or aralkoxycarbonyl, or R.sup.1 and R.sup.2 together form alkylidene, aralkylidene, alkoxycarbonylalkylidene or aralkoxycarbonylalkylidene, wherein either R.sup.3 and R.sup.4, which may be the same or different, each is hydrogen, halogen, hydroxy, amino, nitro, trifluoromethyl, carbamoyl, cyano, alkyl, hydroxyalkyl, cycloalkyl, alkenyl, alkynyl, alkoxy, alkylthio, cycloalkoxy, alkenyloxy, alkynyloxy, alkanoyl, aryl, aryloxy or dialkylamino, or R.sup.3 and R.sup.4 together with the adjacent benzene ring form indanyl, 5,6,7,8-tetrahydronaphthyl, 5-oxo-5,6,7,8-tetrahydronaphthyl, indenyl, 5,8-dihydronaphthyl or naphthyl, wherein either R.sup.5 and R.sup.6, which may be the same or different, each is hydrogen or alkyl, or R.sup.5 and R.sup.6 together with the adjacent pyridazine ring form phthalazinyl, and wherein X is oxygen or --NHCO--, --NHCO--A.sup.1 -- or --NHCO--A.sup.1 --O-- wherein A.sup.1 is alkylene, acid-addition salts thereof, processes for their manufacture and pharmaceutical composition containing them. The compounds p…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.