1-6-naphthyridine derivatives useful in the treatment of blood vessel diseases

US4711901A · kind A · utility

Inventors

• Gerhard Satzinger · Denzlingen, DE
• Johannes Hartenstein · Kirchzarten, DE
• Karl Mannhardt · Hornberg, DE
• Jurgen Kleinschroth · Denzlingen, DE
• Hartmut Osswald · Völklingen, DE
• Gunter Weinheimer · Denzlingen, DE
• Edgar Fritschi · Giengen an der Brenz, DE

Key dates

• Filing date: Jul 30, 1986
• Grant date: Dec 8, 1987
• Expiry date: Jul 30, 2006

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention describes 1,6-naphthyridine derivatives of the general formula: ##STR1## wherein R.sup.1 is an unsubstituted or substituted aromtic or heteroaromatic ring, R.sup.2 is a straight-chained or branched alkyl radical containing up to four carbon atoms or a benzyl radical, R.sup.3 is a hydrogen atom, a straight-chained or branched alkyl radical or an alkoxycarbonyl radical containing up to four carbon atoms, R.sup.4 is a straight-chained or branched alkyl radical containing up to four carbons and R.sup.5 is a carbonyl group or a straight-chained, branched or cyclic alkoxycarbonyl radical which contains up to 17 carbon atoms and optionally also contains an oxygen, sulphur or nitrogen atom; as well as the pharamacologically acceptable salts thereof, which are useful for treating diseases of the blood vessels.