Plasmapheresis system and method
US4713176A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 12, 1985 |
| Grant date | Dec 15, 1987 |
| Priority date | — |
| Expiry date | Apr 12, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M1/3693
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A reliable flow rate plasmapheresis system includes a rotating enhanced vortex of membrane filter coupled to receive a flow of anticoagulated whole blood and separate concentrate and filtrate in response thereto. An anticoagulant pump is coupled to mix controlled amounts of anticoagulant with the input blood flow. Degradation of plasma flow rate during multiple extraction-reinfusion cycles is inhibited by selecting the starting anticoagulant pH value and controlling the anticoagulant flow rate relative to the whole blood to establish a final whole blood/plasma pH value in the range of 6.8 to 7.2, with an anticoagulant to blood ratio in the range of 1:6 to 1:25.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.