Retro-inverso analogs of the bradykinin potentiating peptide BPP.sub.5a
US4713367A · kind A · utility
4Cited by
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7Claims
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Key dates
| Filing date | Jan 22, 1986 |
| Grant date | Dec 15, 1987 |
| Priority date | — |
| Expiry date | Jan 22, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New partially retro-inverso peptides of the following general formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and represent, each independently, the side chain of the aminoacid residues present in the naturally occuring peptides, X is --S--Ph or --O--CH.sub.2 --Ph and Z is a hydroxy, alkoxy or amino group, are described as well as a suitable method for their preparation. The new compounds are useful as antihypertensive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.