Production of optically pure organoboranes
US4713380A · kind A · utility
7Cited by
4References
32Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 16, 1985 |
| Grant date | Dec 15, 1987 |
| Priority date | — |
| Expiry date | Jan 16, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for upgrading to essentially 100% enantiomeric excess the optical purity of an organoborane intermediate represented by the formulae: EQU IcpBHR* or EQU Icp.sub.2 BR* wherein Icp is isopinocampheyl and R* is a unsubstituted or substituted, acyclic or cyclic alkyl having from 4 to 30 carbon atoms, comprising the steps of hydroborating cis-alkene, a trans-alkene or a tertiary-alkene with monoisopinocampheylborane or diisopinocampheylborane, obtaining a solid organoborane and recrystallizing the solid organoborane to obtain an enantiomeric excess of essentially 100% ee of said organoborane.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.