Patent · US Expired

Cyclic derivatives of alkyl dihydroxyalkylxanthenes

US4713455A · kind A · utility

12Cited by
2References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 4, 1986
Grant dateDec 15, 1987
Priority date
Expiry dateApr 4, 2006

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D473/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the formula ##STR1## wherein one of the radicals R.sup.1, R.sup.2 or R.sup.3 denotes a straight-chain alkyl group having 4 to 8 C atoms and two vicinal hydroxyl groups in the .omega.,.omega.-1 or .omega.-1,.omega.-2 positions and the two other radicals represent straight-chain or branched alkyl groups having up to 12 C atoms in the position of R.sup.1 and R.sup.3 and up to 4 C atoms in the position of R.sup.2, the total of C atoms in these two alkyl substituents being a maximum of 14, are prepared by oxidation of the corresponding alkenylxanthines and by alkylation with compounds which introduce the dihydroxyalkyl radical or a precursor thereof. The dihydroxyalkyldialkylxanthines are suitable for the treatment of obstructive respiratory tract diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.