Quadroma cells and trioma cells and methods for the production of same
US4714681A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 18, 1984 |
| Grant date | Dec 22, 1987 |
| Priority date | — |
| Expiry date | Jun 18, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/948
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antibodies having binding affinity for two desired antigens, hereinafter "recombinant monoclonal antibodies"; recombinant monoclonal antibodies produced by a quadroma cell or a trioma cell; and methods for producing recombinant monoclonal antibodies by means of a quadroma cell or a trioma cell, wherein a quadroma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a hybridoma cell which produces an antibody having specific binding affinity for another desired antigen, and wherein a trioma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a lymphocyte which produces an antibody having specific binding affinity to another desired antigen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.