2-alkoxy-N-(1-azabicyclo(2.2.2)oct-3-yl) benzamides and thiobenzamides in a method for alleviating emesis caused by non-platinum anticancer drugs
US4717563A · kind A · utility
11Cited by
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13Claims
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Key dates
| Filing date | Mar 5, 1986 |
| Grant date | Jan 5, 1988 |
| Priority date | — |
| Expiry date | Mar 5, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of controlling emesis caused by non-platinum anti-cancer drugs with 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides having the formula ##STR1## wherein X is oxygen or sulfur; R.sub.1 is loweralkyl; and R.sub.2 is selected from the group consisting of hydrogen, halo, 4,5-benzo, methylsulfonyl, loweralkoxy or Am and n is 1 or 2, and the pharmaceutically acceptable acid addition salts thereof is disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.