Synthetic urogastrone gene, corresponding plasmid recombinants, transformed cells, production thereof and urgastrone expression
US4719180A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 13, 1984 |
| Grant date | Jan 12, 1988 |
| Priority date | — |
| Expiry date | Sep 13, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/12
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A synthetic gene characterised in that it codes for the expression of urogastrone or a sub-unit thereof is disclosed. The production thereof by the assembly and ligation of a number of nucleotide blocks is also disclosed, as are corresponding plasmid recombinants, transformed cells and the production thereof. The expression of urogastrone is further disclosed. Urogastrone is a polypeptide hormore (protein) which may be isolated in small amounts from human urine. It has an application in the treatment of ulcers and in the promotion of wound healing. The present invention provides a more viable commercial production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.