Patent · US Expired

Manufacture of hollow fine tubular drug delivery systems

US4720384A · kind A · utility

84Cited by
15References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 21, 1986
Grant dateJan 19, 1988
Priority date
Expiry dateAug 21, 2006

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/0092
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Pharmaceutical compositions are provided which contain hollow fine tube drug delivery systems. The compositions comprise a pharmaceutically suitable carrier, preferably in the form of a capsule, tablet, suspension, or suppository, and at least one drug delivery system which consists essentially of (1) a polymeric tube having a membrane outer sheath and a hollow core, and (2) at least one drug compound contained within the core, said system contained in the composition in an amount sufficient to deliver a therapeutic amount of the drug contained therein at a predetermined rate over a predetermined period of time. By varying the polymer, the permeability of the outer sheath, the drug, the drug concentration in the hollow core of the tube, the tube diameter, the tube length, the tube core diameter, and the sealing of the tube ends, a wide variety of drug therapeutic amounts, rates and dosing times can be achieved.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.