Pyridotriazoloquinazolines and triazolopyridoquinazolines useful as antiallergics

US4720496A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Kurt Schromm · Ingelheim am Rhein, DE
• Anton Mentrup · Mainz, DE
• Ernst-Otto Renth · Ingelheim am Rhein, DE
• Armin Fugner · Gau-Algesheim, DE

Key dates

• Filing date: Jun 4, 1986
• Grant date: Jan 19, 1988
• Expiry date: Jun 4, 2006

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein (a) PA1 R.sub.1 is hydrogen, lower alkyl, lower alkoxy or 8-halo; PA1 R.sub.2 is hydrogen, lower alkyl, lower alkoxy or a fused benzene ring; and PA1 R.sub.3 and R.sub.4, together with each other, are --N.dbd.N--NH--; or PA0 (b) PA1 R.sub.1 and R.sub.2, together with each other, are --N.dbd.N--NH--; PA1 R.sub.3 is hydrogen, lower alkyl, lower alkoxy, 2-halo, 3-halo or 4-halo; and PA1 R.sub.4 is hydrogen, lower alkyl, lower alkoxy or a fused benzene ring; and non-toxic, pharmacologically acceptable salts thereof formed with an inorganic or organic base. The compounds as well as their salts are useful as antiallergics.