Steroidal liposomes
US4721612A · kind A · utility
136Cited by
11References
57Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 10, 1985 |
| Grant date | Jan 26, 1988 |
| Priority date | — |
| Expiry date | Apr 10, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/117497
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are described for the preparation of lipid vesicles, the bilayers of which comprise a salt form of an organic acid derivative of a sterol such as the tris-salt form of a sterol hemisuccinate. The method is rapid, efficient, and does not require the use of organic solvents. The sterol hemisuccinate vesicles may be used to entrap compounds which are insoluble in aqueous solutions. Such preparations are especially useful for entrapping bioactive agents of limited solubility thus enabling administration in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.