4-cyanopiperidine derivatives
US4721788A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 8, 1986 |
| Grant date | Jan 26, 1988 |
| Priority date | — |
| Expiry date | Jul 8, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/62
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel 4-cyanopiperidine derivative, which is represented by the following general formula (I): ##STR1## wherein X means a halogen atom, or an acid addition salt thereof, is prepared by reacting N-(2-hydroxyethyl)-4-carbamoylpiperidine or an acid addition salt thereof with a dehydrating and halogenating agent; or by reacting 4-cyanopiperidine or a salt thereof with a compound represented by the following general formula (IV): EQU X--CH.sub.2 CH.sub.2 --Y (IV) wherein X has the same meaning as defined above and Y denotes the same halogen atom as X or another halogen atom. The derivative is useful as intermediate for synthesis of quinuclidine derivative which is in turn useful as intermediate for the production of medicines, chemicals, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.