Patent · US Expired

Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase

US4722927A · kind A · utility

9Cited by
0References
6Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 28, 1986
Grant dateFeb 2, 1988
Priority date
Expiry dateApr 28, 2006

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D239/52
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Certain disubstituted pyrimidineamides of oleic and linoleic acids are potent inhibitors of the enzyme acyl-CoA:cholesterol acyltransferase and are thus useful agents for inhibiting the intestinal absorption of cholesterol.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.