Patent · US Expired

Antifungal pastille formulation and method

US4725440A · kind A · utility

35Cited by
4References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 24, 1984
Grant dateFeb 16, 1988
Priority date
Expiry dateMay 24, 2004

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/0056
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An antifungal pastille formulation, preferably containing nystatin as the antifungal agent, is provided which is soft and smooth in texture and when dissolved slowly in the mouth does not cause irritation of and will not adhere to oral mucosa and yet distributes nystatin in sufficiently high saliva concentrations, throughout the oral cavity, for long enough periods of time so as to be particularly effective in the treatment of candidiasis in the oral cavity and esophagus. A method for treating candidiasis in the oral cavity and esophagus employing the antifungal pastille and a method for preparing a nystatin pastille formulation are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.