Plasma fraction purification using silica resin bound to a ligand
US4725673A · kind A · utility
16Cited by
11References
28Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 29, 1986 |
| Grant date | Feb 16, 1988 |
| Priority date | — |
| Expiry date | Aug 29, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/83
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
There is provided, in accordance with practice of this invention, a process for separating Factor IX and/or Factor X from an impure protein fraction containing protein in addition to Factors IX and X. A silica resin coupled with a ligand capable of binding Factor IX and/or Factor X is provided. An aqueous solution of the impure protein fraction is applied to the ligand-coupled silica resin to thereby bind the Factor IX and/or Factor X to the resin. The Factor IX and/or Factor X is then recovered from the resin by elution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.