Fibronectin solution suitable for use in humans and process for its preparation
US4727059A · kind A · utility
28Cited by
13References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 24, 1986 |
| Grant date | Feb 23, 1988 |
| Priority date | — |
| Expiry date | Nov 24, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A fibronectin injectable solution is made by recovering a fibronectin-containing raw material which is solubilized, provided with stabilizers and then subjected to an initial heat treatment at 57.degree. to 60.degree. for at least ten hours. After fibronectin concentration and the addition of further stabilizers and plasma-protein vehicle, the solution is again subjected to a temperature of 60.degree. for ten hours to provide an injectable solution which is free from virulent hepatitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.