Certain anti-hypertensive 2,3-dihydrobenzofuran compounds
US4727086A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 30, 1986 |
| Grant date | Feb 23, 1988 |
| Priority date | — |
| Expiry date | Jun 30, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to 2,3-dihydrobenzofuran derivatives of the general formula: ##STR1## in which: each of X.sub.1 and X.sub.2, which are identical or different, represents a hydrogen or halogen atom or an alkoxy radical containing from 1 to 4 carbon atoms, PA0 X.sub.3 represents a hydrogen atom or an alkyl radical having from 1 to 4 carbon atoms, PA0 Y represents a hydrogen atom or a hydroxy radical, each of R.sub.1 and R.sub.2, which are identical or different, represents an alkyl radical having from 1 to 4 carbon atoms, PA0 or R.sub.1 represents a methyl radical and R.sub.2 represents a phenylalkyl grouping or a 2-indanyl grouping, each of which may be substituted or unsubstituted, PA0 or R.sub.1 and R.sub.2 together form, with the nitrogen atom to which they are attached, a piperazinyl radical, a tetrahydroisoquinolyl radical, a morpholinyl radical or a tetrahydrothienopyridinyl radical. The compounds are useful in the treatment of hypertension.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.