Retinoid composition having enhanced bioavailability and percutaneous absorption
US4727088A · kind A · utility
27Cited by
2References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 15, 1986 |
| Grant date | Feb 23, 1988 |
| Priority date | — |
| Expiry date | Dec 15, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new and improved topically applied pharmaceutical preparation for the treatment of acne and an improved vehicle for delivering the active ingredients thereof to the human skin in a manner whereby the bioavailability and percutaneous absorption of the active ingredient is remarkably enhanced. The vehicle comprises a volatile silicone, a fatty alcohol having from 12-22 carbon atoms, retinoids selected from the group consisting of tretinoin (all-trans retinoic acid) and isotretinoin (13-cis retinoic acid); and such preservatives or emulsifying agents as may be warranted.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.