Formulations providing three distinct releases
US4728512A · kind A · utility
135Cited by
17References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 4, 1986 |
| Grant date | Mar 1, 1988 |
| Priority date | — |
| Expiry date | Mar 4, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5073
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A therapeutic preparation consisting of three groups of spheroids containing an active medicinal substance. The first group of spheroids is uncoated and rapidly disintegrates upon ingestion to release an initial dose of medicinal substance a second group of spheroids is coated with a pH sensitive coat to provide a second dose and a third group of spheroids is coated with a pH independent coat to provide a third dose. A powder blend of active medicinal substance may be substituted for the first group of uncoated spheroids. The therapeutic preparation may be utilized as a mixture of groups of spheroids in a capsule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.