Granular delayed-release form of pharmaceutically active substances
US4728513A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jul 23, 1986 |
| Grant date | Mar 1, 1988 |
| Priority date | — |
| Expiry date | Jul 23, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5026
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A granular delayed-release form of pharmaceutically active substances, which is prepared by coating a granulated or crystalline pharmaceutically active substance, or mixtures thereof, with a coating material mixture consisting essentially of a homogeneous mixture of a poly(H+meth)-acrylic acid-(methyl+ethyl)ester which is insoluble but dispersible in water and an ethyl cellulose which is insoluble but dispersible in water in the weight ratio of 20:1 to 1:5, is presented, which is characterized by the fact that the coated granules are heated for at least 5 minutes at elevated temperatures ranging from between 50.degree. to 120.degree. C.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.