Patent · US Expired

2-substituted thio or oxy-4-aryl or heterocyclo-5-carboxy-1,4-dihydropyrimidines, composition containing them, and method of using them to reduce blood pressure

US4728652A · kind A · utility

18Cited by
10References
23Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 21, 1986
Grant dateMar 1, 1988
Priority date
Expiry dateApr 21, 2006

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

1,4-Dihydropyrimidines of the formula ##STR1## wherein X is sulfur or oxygen and R.sub.4 is aryl or heterocyclo and disclosed. These compounds are useful as cardiovacular agents, particularly anti-hypertensive agents, due to their vasodilator activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.