Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
US4729985A · kind A · utility
9Cited by
3References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 30, 1986 |
| Grant date | Mar 8, 1988 |
| Priority date | — |
| Expiry date | Apr 30, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/86
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A series of novel polypeptide derivatives, containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues, which are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin. Particularly valuable precursors for many of these compounds are certain other 5-amino-2,5-disubstituted-4-hydroxypentanoic acid derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.