Coumarin derivatives and antiallergic agents containing the same
US4731375A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 9, 1985 |
| Grant date | Mar 15, 1988 |
| Priority date | — |
| Expiry date | Dec 9, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A chromene derivative having the general formula (I): ##STR1## wherein n is 1 to 5 and --O--CH.sub.2).sub.n CO.sub.2 H group is attached to 5-position, 6-position, 7-position or 8-position, or salts thereof, a process for preparing the same and antiallergic agents containing the same. The compounds of the present invention inhibit the immunological release of chemical mediators such as SRS-A and histamine from mast cell and have an excellent effect in preventing and treating the various allergic diseases such as allergic asthma, allergic dermatitis, allergic nasitis, hives, allergic enteritis and allergic conjunctivitis, especially allergic asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.