N-sulfamyl-3-halopropionamidines
US4731479A · kind A · utility
2Cited by
1References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 10, 1986 |
| Grant date | Mar 15, 1988 |
| Priority date | — |
| Expiry date | Sep 10, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/48
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new propionamidine derivatives of formula (I) ##STR1## wherein X is halogen, and to a process for their preparation. According to the invention compounds of the formula (I) are prepared by reacting a 3-halopropionitrile of the formula (III) ##STR2## wherein X is as defined above, with sulfamide of the formula (II) ##STR3## in the presence of a hydrogen halide. Compounds of the formula (I) are useful intermediates in the preparation of famotidine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.