Patent · US Expired

Octahydronaphthalene derivatives and their preparation

US4733003A · kind A · utility

18Cited by
1References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 6, 1986
Grant dateMar 22, 1988
Priority date
Expiry dateMay 6, 2006

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula (I): ##STR1## [wherein X represents a hydrogen atom or a 2-methylbutyryl group, Y represents a hydrogen atom or a methyl group and R.sup.1 and R.sup.2 are the same or different and each represents an oxygen atom or a group of formula .dbd.N--OR.sup.3 (wherein R.sup.3 represents a hydrogen atom or an alkyl group)], the free hydroxy-carboxylic acids corresponding thereto and salts and esters of said acids may be prepared by oxidizing and, if necessary, oximating a corresponding ML-236A, ML-236B, MB-530A or MB-530B compound, and these compounds have valuable antihypercholesteraemic activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.