N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxome thyl]-N-methylglycine S-oxide and the amide thereof
US4734435A · kind A · utility
3Cited by
8References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 25, 1986 |
| Grant date | Mar 29, 1988 |
| Priority date | — |
| Expiry date | Nov 25, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/205
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxomethyl]-N-methylgl ycine S-oxide (tolrestat S-oxide) and the amide thereof and methods of their preparation. The S-oxides are new aldose reductase inhibitors useful for the treatment of prevention of diabetic complications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.