Immune system-stimulating N-glycosylated ureas and carbamates

US4737488A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Oswald Lockhoff · Cologne, DE
• Bernd-Wieland Kruger · Wittlich, DE
• Peter Stadler · Haan, DE
• Karl G. Metzger · Wuppertal, DE
• Hans-Georg Opitz · Weinheim, DE
• Klaus Schaller · Wuppertal, DE
• Klaus G. Stunkel · Wuppertal, DE
• Hans-Joachim Zeiler · Velbert, DE

Key dates

• Filing date: Nov 29, 1984
• Grant date: Apr 12, 1988
• Expiry date: Nov 29, 2004

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H15/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein R.sup.1 is hydrogen, an optionally substituted aromatic hydrocarbon radical, an aralkyl radical or an optionally substituted aliphatic hydrocarbon radical having up to 45 C atoms, PA1 R.sup.2 is an optionally substituted aromatic hydrocarbon radical, an aralkyl radical or an optionally substituted aliphatic hydrocarbon radical having 5-50 C atoms, PA1 X is O, S, NH or NR, R being an alkyl radical having up to 20 C atoms, and PA1 Z is a glycosyl radical bonded via the anomeric carbon atom, or pharmaceutically acceptable salts thereof stimulate the immune system.