Veterinary implant
US4738679A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 26, 1985 |
| Grant date | Apr 19, 1988 |
| Priority date | — |
| Expiry date | Sep 26, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of regulating the reproductive functions of animals, preferably domesticated ruminants, and veterinary implants for use in such a method are provided. The veterinary implant tablet comprises about 2-15% by weight of a fatty acid salt compression binder, about 25-50% by weight of a directly compressible vehicle selected from the group consisting of calcium phosphate and derivatives thereof, about 1-5% by weight of a granulating agent, and an amount of melatonin effective to maintain blood melatonin at, or above, a natural nighttime level of an animal to be treated for a period of time effective to accelerate an onset of breeding activity in mature animals or to delay an onset of puberty in prepubescent animals. The implant tablet provides a substantially continuous release rate of melatonin so as to maintain blood melatonin at, or above, the stated level. A method for preparing such a veterinary implant tablet is also described. A method of modifying the seasonal breeding activity of animals is also provided which comprises administering to an animal to be treated the disclosed veterinary implant tablet.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.