1,3,4-Thiadiazole derivatives and pharmaceutical preparations useful as inhibitors for histamine-H.sub.2 receptors

US4738960A · kind A · utility

Assignee

• Ludwig Heumann & Co. GmbH · DE

Inventors

• Helmut Schickaneder · Eckental, DE
• Rolf Herter · Schwabach, DE
• Kurt Wegner · Mainz, DE
• Walter Schunack · Berlin, DE
• Istvan Szelenyi · Arnstorf, DE
• Stefan Postius · Konstanz, DE
• Kurt H. Ahrens · Nürnberg, DE

Key dates

• Filing date: Nov 19, 1985
• Grant date: Apr 19, 1988
• Expiry date: Nov 19, 2005

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

1,3,4-Thiadiazole derivatives corresponding to the general formula I ##STR1## which constitute highly effective inhibitors for histamine-H.sub.2 receptors are described. These compounds in addition have a cytoprotective action.