Process for converting organo-hydroxyl compounds to halides
US4739057A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 30, 1986 |
| Grant date | Apr 19, 1988 |
| Priority date | — |
| Expiry date | Jun 30, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/61
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for converting organic hydroxyl-containing compounds to halides which comprises reacting the hydroxyl-containing compound with a phosphorushalide reagent of formula: R.sub.n PX.sub.5-n wherein n is selected from 1, 2 and 3; R is selected from the group consisting of C-6 to C-10 aryl and substituted aryl wherein the substituents are selected from the group consisting of straight and branched chain alkyl, alkoxy, and haloalkyl, halogen, sulfonate and mixtures thereof; and X is a halogen. It is preferred to carry out the reaction in the presence of an arylphosphorusoxydihalide solvent. The use of an arylphosphorustetrahalide and particularly phenylphosphorustetrachloride is preferred. The arylphoshorustetrahalide can be prepared in situ by contacting a solution of the corresponding arylphosphorusdihalide in an arylphosphorusoxydihalide solvent with a halogen. The process can further comprise the step of heating the reaction mixture. Maintaining a reaction temperature of from about 0.degree. C. to about 150.degree. C. for from about 1 hour to about 24 hours is preferred.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.