Production of cellulose dialysis membrane with improved biocompatibility
US4741927A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 16, 1986 |
| Grant date | May 3, 1988 |
| Priority date | — |
| Expiry date | May 16, 2006 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D71/12
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention relates to a method for the production of a dialysis membrane of regenerated cellulose. Isocyanate prepolymers with an average molecular weight of 300 to 50,000, which are soluble in organic solvents other than solvents reacting with isocyanate groups and dissolving cellulose, are bound chemically at least to one membrane surface of the dialysis membrane. The dialysis membrane made by the process of the present invention substantially eliminates the symptoms of leukopenia and complement activation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.